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www.expresspharmaonline.com FORTNIGHTLY INSIGHT FOR PHARMA PROFESSIONALS
16-31 August 2008  
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South India—An attractive emerging pharmaceutical hub

A report from Interlink Business Consultancy and Confederation of Indian Industries (CII)

South India is emerging as a strong pharma hub with a vibrant IT industry and strong infrastructure of research facilities and scientists.

South India—A snapshot

Several MNCs are starting research operations in South India, turning the region into a pharmaceutical services hotspot. Drug trials expenditure in India is expected to reach $1.5 billion by 2010, with South garnering a significant portion of this business. Hyderabad, Chennai and Bangalore are being viewed as important in sourcing centres.

South India is an attractive destination since it offers availability of scientific and technical expertise, academic research facilities, environment conducive to innovation and credibility, English language and competitive compensation. South India's expertise in IT skills combined with strong knowledge in pharma domain is ideal for drug development and clinical research activities.

Business potential of South India

  • Bio-cluster

Bangalore is being recognised as a bio-cluster. The creation of economic clusters of biotech units is attributable to increasing returns under monopolistic competition and generation of strategic alliances. Leading companies in Karnataka include Accelrys, Advinus Therapeutics, Agilent Technologies, Animal Biotech, Automed Systems, Avesthagen, Bharat Biotech, Bigtec, Biocon, ClinTec (India) International, CytoGenomics, Delta Biologicals etc. The State's biotech ventures are sustained by the presence of notable research institutes like Indian Institute of Science (IISc), National Centre for Biological Sciences (NCBS) and Jawaharlal Nehru Centre for Advanced Research (JNCAR). There is also a large presence of pharmacy-biotech graduates.

Karnataka has emerged as a centre for generics, medical devices, biotech and drug discovery. The total pharma market in the State in 2006 was Rs 1,317 crore with 251 companies in the fray. The industry is growing at 17.82 percent. The State is active in pharma services such as bioinformatics research support services. It accounted for 55 percent of biotech companies in the country in 2006-07.

Out of a total 320 enterprises in India, Karnataka has 175 units and 158 of these are located in Bangalore.

In 2005-06, out of the 28 new biotech ventures, 27 were set-up in Karnataka. In 2005-06, the State biotech business registered a turnover of Rs 1,400 crore. Exports generated revenues to the tune of Rs 850 crore. The total scientific head count was 6,800 personnel. The presence of sophisticated corporate hospital chains in Bangalore is turning Karnataka into an important healthcare hub. Companies like GP, Wipro, Biocon, AstraZeneca, Nova Nordisk, Lumbeck, AFD and Manipal hospitals are playing a major role here.

  • Bulk drugs

Andhra Pradesh is active in bulk drugs production and biotech. The State also specialises in offering CRM solutions since it is an IT hub. It has several important institutions such as Pharmexcil, Shapoorji Biotech Park and a knowledge park promoted by ICICI.

Andhra Pradesh alone contributes 9.5 percent to total Indian pharma market. The pharma market in the State is estimated to be Rs 2,900 crore growing at the rate of 14 percent. The total market size of therapeutic segments like anti-diabetes is Rs 130 crore, cardiology is Rs 331 crore, PPI is Rs 130 crore, antihistamines is Rs 51 crore, gynaecology (nutraceuticals like calcium and iron preparations) is Rs 94 crore, and antibiotics groups like Macrolide is Rs 44 crore.

Key players in the State include Dr Reddy's Laboratories, Aurobindo Pharma, Natco Pharma, Suven Pharmaceuticals, Biological E, Divi's Labs, Matrix Laboratories, Hetero Drugs, Neuland Laboratories, Global Bulk Drugs and Fine Chemicals and Glochem Industries.

Andhra Pradesh accounts for more than one-third of India's total bulk drug production. A major share of the bulk drugs produced by State based companies find their way to foreign markets, resulting in high export turnover from the segment. The State has emerged as a key player not only in the export of bulk drugs but also finished formulations. It has set a production target of $8 billion by 2010 and between $10-15 billion by 2020 from the pharma sector.

Good infrastructure facilities, availability of trained manpower combined with the presence of leading research and development centres like CCMB, IICT, CDFD, NIN etc make the State a fertile land for the industry to take deep roots and flourish.

Figure 1: Break-up of enterprises in India

  • Manufacturing

The pharma industry in Tamil Nadu is undergoing a critical phase in its evolution. It is facing closure of several units owing to inability to comply with Schedule M norms besides the issue of migration of units to excise free zones (EFZ). The industry in the State is banking on the proposed setting up of EFZs and SEZs to boost industrial growth. The small scale industry (SSI) is pinning hopes on the cluster development programme to promote infrastructure development and boost growth. The industry also expects support from the Central Government for technological upgradation of the pharma cluster at Alathur with new facilities for R&D and industrial development.

Several retail pharmacy chains have opened up in Tamil Nadu. The mushrooming of organised retail medical shops in the State has led to efforts by traditional medical shops and their associations to improve quality of service to take on the new trend. These include Macare, a company floated by the Kerala based Manappuram group and LifeKen, promoted by Lifetime Healthcare.

Several contract research organisations are in the process or intending to set up facilities in South India. These include Quintiles, Parexel, Actavis and Indian companies such as Aurigene, Clinigene and Asian Clinical Trials.

Tamil Nadu is active in both ayurveda and healthcare. The State was the fourth largest producer of medicines in the country in 2006 after Maharashtra, Gujarat and Andhra Pradesh. It has several organised retail pharmacy chains. The setting up of export free zones such as the proposed 250 acre Nanguneri Pharma Park can impart a boost to the pharma industry in the State.

  • Ayurveda and spas

Kerala has been globally recognised for its ayurvedic treatments, ayurvedic research and herbal spas with names like Kaya Kalp. The intensity of ayurvedic medicines has been deep rooted throughout Kerala. As a result, State organisations such as Kottakal Pharma have Rs 7,100 crore turnover in only one state.

The marketing methodologies in Kerala also explore media, newspapers and other digital media to promote ayurvedic and herbal products throughout Kerala.

Besides being prominent in ayurveda, ayurvedic research and necessary distribution channels have been fully well established so that citizens from Kerala can access the products with affordability. Similarly research centre in ayurveda as well as destination spas have encompassed and invigorated human life at different destinations in Kerala.

Nagarguna Herbals, Kottakal and other clusters of ayurvedic companies are key players in Kerala.

South India: SWOT analysis

Strengths

  • Support from quality infrastructure and scientific institutions.
  • Emergence of South India as an IT hub.
  • Availability of skilled scientific manpower.
  • Economic and regulatory climate conducive to innovation.
  • Strong capabilities in manufacture of bulk drugs and formulations.

Weaknesses

  • Effective sales force for marketing.
  • Demand supply gap for biotech and CRO professionals

Opportunities

  • Opportunities for export of bulk drugs in emerging markets.
  • Emergence of biotechnology sector in the region.
  • Opportunities in CRAMS, CROs and clinical trials.
  • Opportunities for foray into global market through strategic acquisitions, joint ventures and expansion and upgradation.

Threats

  • Migration of units to EFZs.
  • Challenges posed by globalisation such as closure of units owing to inability to comply with Schedule M norms.
  • Challenges posed for Indian system of medicine due to compliance with Schedule T.

Interlink's perspective—Bridging gaps to maximise potential

Growth of pharma industry in South India is hampered by absence of linkages between industry value chain parameters. This paradox exists despite abundance of skilled scientific manpower for scientific research and a vibrant IT industry which supplements and adds value to the efficiency of the pharma industry. The presence of a strong and vibrant ayurvedic industry suffuses and hampers the penetration of allopathy in the region.

SMEs (small and medium enterprise)

Lack of entrepreneurship, ambition, drive and initiative hamper the growth of industry despite presence of requisite resources and infrastructure. Industry faces a critical funding constraint despite presence of several foreign banks and financial institutions because of lack of initiative and drive to avail these facilities. Lack of skilled manpower for marketing also hampers efforts aimed at market penetration in the region.

Conclusion

The pharma value chain of South India in Figure 2 describes the strategic options available for achieving long term sustainable growth and unlocking the huge potential provided they are linked together to create value.

Southern region of India has grown steadily in the recent years and is emerging as one of the most developed regions of the pharmaceutical industry. The benefits afforded by the significant cost-savings opportunities and highly skilled work force, however, are tempered by the challenges this region faces.

(The report is authored by Dr Raja B Smarta, Founder and Managing Director, Interlink Business Consulting Firm, with inputs from CII and Express Pharma)

 


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